Best Memetics Specializations Tier List | Once Human|Game8 (2025)

Best Memetics Specializations Tier List | Once Human|Game8 (1)

The best Memetic Specializations to take in Once Human include Electrolysis, Precision Refining, and Sulfur Chemist. Read on for a best Memetic Specializations tier list and what they do in this guide.

Best Memetics Specializations Tier List | Once Human|Game8 (2)Attention! This page is being updated as more Memetics Specializations are discovered, stay tuned for more!

List of Contents

  • Memetics Specializations Tier List
  • Best Specializations Explained
  • How to Get
  • Related Guides
All Memetics Specialization Guides
All Memetics Specializations List Best Memetics Specializations

Memetics Specializations Tier List

Best Memetics Specializations Tier List
Tier Memetics Specializations
Best Memetics Specializations Tier List | Once Human|Game8 (3)

Best Memetics Specializations Tier List | Once Human|Game8 (4)Electric Furnace: Electrolysis

Best Memetics Specializations Tier List | Once Human|Game8 (5)Furnace: Precision Refining

Best Memetics Specializations Tier List | Once Human|Game8 (6)Sulfur Chemist

Best Memetics Specializations Tier List | Once Human|Game8 (7)

Best Memetics Specializations Tier List | Once Human|Game8 (8)Pickaxe: Moonlight Mining

Best Memetics Specializations Tier List | Once Human|Game8 (9)Solar Drill

Best Memetics Specializations Tier List | Once Human|Game8 (10)Precious Metal Refining

Rare Crystal Set

Combo Chipset

Best Memetics Specializations Tier List | Once Human|Game8 (11)

Best Memetics Specializations Tier List | Once Human|Game8 (12)Backpack Expansion

Best Memetics Specializations Tier List | Once Human|Game8 (13)Deluxe Storage Crate

Best Memetics Specializations Tier List | Once Human|Game8 (14)Solar Generator: Photon Power

Best Memetics Specializations Tier List | Once Human|Game8 (15)Hydraulic Generator: One with the Tides

Best Memetics Specializations Tier List | Once Human|Game8 (16)Supplies Workbench: Healing Boost

Best Memetics Specializations Tier List | Once Human|Game8 (17)

Best Memetics Specializations Tier List | Once Human|Game8 (18)Electric Furnace: Efficiency Lover

Best Memetics Specializations Tier List | Once Human|Game8 (19)Electric Drill: Treasure Hunter

Crystal Transformation

Best Memetics For General Purposes

This is a tier list for the best Memetics Specializations for general game progression in Once Human. As the options provided when levelling up are random, players are not always guaranteed to find these in the pool.

Players may also find that other Specializations suit their playstyles better than those listed here. If you have suggestions for Memetics Specializations to be included, drop it in the comments below!

All Memetics Specializations List

Best Specializations Explained

SS Tier Memetics Specializations

Memetics Specialization Tier List
Jump to any tier!
Memetics Specialization Explanation
Best Memetics Specializations Tier List | Once Human|Game8 (24)Electric Furnace: Electrolysis ・Doubles yield when smelting Aluminum and Tungsten in an Electric Furnace
・Massively improves late-game ingot generation
Best Memetics Specializations Tier List | Once Human|Game8 (25)Furnace: Precision Refining ・Reduces resource consumption and smelting time for certain ores at a Furnace or Electric Furnace
・Improves the yield when smelting Copper, Bronze, Steel, Aluminum, and Tungsten to ingots
Best Memetics Specializations Tier List | Once Human|Game8 (26)Sulfur Chemist ・Can use Sulfur and Energy Link to make Acid at Synthesis Bench
・Simpler production method for farming an important resource

Game-Changing Memetics Specializations

Memetics Specializations in this tier can massively improve what players can do in-game.

Big boosts to product yield, reduced costs for item creation, and new recipes to create important items that would be difficult to farm otherwise are just some examples of what specializations in this tier can achieve.

S Tier Memetics Specializations

Memetics Specialization Tier List
Jump to any tier!
Memetics Specialization Explanation
Best Memetics Specializations Tier List | Once Human|Game8 (31)Pickaxe: Moonlight Mining ・Increased yield when mining Copper, Tin, Iron, Aluminum, and Tungsten with a pickaxe, doubled at night
・Big yield increase to mining raw ore
Best Memetics Specializations Tier List | Once Human|Game8 (32)Solar Drill ・Electric Drill now charges on sunny days and provides increases to ore yield for Copper, Tin, Iron, Aluminum, and Tungsten
・Upgrades a renewal tool to no longer need batteries, and now boosts yield
Best Memetics Specializations Tier List | Once Human|Game8 (33)Precious Metal Refining ・Smelt Gold and Silver ore into ingots using a Furnace
・Provides access to Gold and Silver ingots that sell for a lot of Energy Links
Rare Crystal Set ・Use crystals at a Furnace to make a Rare Crystal Set
・Grants access to the Rare Crystal Set, which can sell for a lot of Energy Links
Combo Chipset ・Turn electronic parts, metal scrap, and parts into a Combo Chipset
・Gives the recipe for Combo Chipset, an item that can be sold for lots of Energy Links

Very Helpful Specializations to Have

While not as powerful as those in the tier above, these specializations still provide helpful effects that can range from ore yield increases, to methods of farming Energy Links using various types of materials.

A Tier Memetics Specializations

Memetics Specialization Tier List
Jump to any tier!
Memetics Specialization Explanation
Best Memetics Specializations Tier List | Once Human|Game8 (38)Backpack Expansion ・Craft an item that increases max load when in the inventory
・Quality-of-life update for general gameplay, especially resource gathering
Best Memetics Specializations Tier List | Once Human|Game8 (39)Deluxe Storage Crate ・Grants access to a recipe for a Storage Crate with 64 slots
・Quality-of-life upgrade for storage and organizing
Best Memetics Specializations Tier List | Once Human|Game8 (40)Solar Generator: Photon Power ・Solar Generator Power Output + 10w
・Increases the facility's power generation, meaning more room and electricity for facilities that need power
Best Memetics Specializations Tier List | Once Human|Game8 (41)Hydraulic Generator: One with the Tides ・Maximum number of generators +1, also increases power output depending on water flow
・Grants another generator facility and improves existing ones for even more electricity in the base
Best Memetics Specializations Tier List | Once Human|Game8 (42)Supplies Workbench: Healing Boost ・HP recovery +10% and output +1 when crafting Activators
・Boost the generation of healing items, also heals the player upon crafting healing items

Specializations With Noticeable Benefits

Memetics Specializations in this tier can provide noticeable quality-of-life upgrades that make them worth exploring as an option.

B Tier Memetics Specializations

Memetics Specialization Tier List
Jump to any tier!
Memetics Specialization Explanation
Best Memetics Specializations Tier List | Once Human|Game8 (47)Electric Furnace: Efficiency Lover ・Decrease Electric Furnace power consumption and smelting times
・Boosts the processing speed at Electric Furnaces while opening up some electricty allotment for other facilities
Best Memetics Specializations Tier List | Once Human|Game8 (48)Electric Drill: Treasure Hunter ・Increases the yield of Gold, Silver, and Stardust Ore when mined with an Electric Drill
・Needs other Specializations that use the aforementioned ores to shine
Crystal Transformation ・Turn Stardust Source and alloy ingots into different Crystals at a Furnace
・Handy for getting specific crystals, but uses Stardust Source, which can be difficult to resupply

Specializations That Provide Minor Benefits

Specializations in this tier either provide minor benefits, need other specializations to shine, or use materials that are already being competed for in other processes. They can work, but players need to be aware of the downsides.

How to Get Memetics Specializations

Given Every Five Levels

Best Memetics Specializations Tier List | Once Human|Game8 (49)

Players can select a new Memetic Specialization every 5 levels that they gain. These Specializations can be found in the Memetics menu, near the top-left corner of the screen.

Options Provided Are Random

Best Memetics Specializations Tier List | Once Human|Game8 (50)

Every time a player goes to select a new Memetic Specialization, they are provided with 4 randomized choices from the Specialization pool available at that level.

As these options are randomly generated, players are not guaranteed to find the Specializations listed above. However, players can choose to reset a Memetic Specialization with a Specializations Cleaner.

Once Human Related Guides

Best Memetics Specializations Tier List | Once Human|Game8 (51)

Tips and Tricks: Beginner's Guide

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How to Get and Use the Wish Machine How to Change Worlds
Lucky Roulette: Where and How to Use It Cargo Scramble Guide
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The Wanderer: Bus Monster Guide How to Get Deviant Toys
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How to Join PvP -
Tier Lists
Best Weapons Tier List Memetics Specializations Tier List
Best Deviants Best Crops to Grow
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How to Get Lightforge Medals -
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Attack on Map Icon Meaning Eternaland Explained
What is the Max Level? How to Delete Your Character
What Are Damaged Data Discs For? -
Best Memetics Specializations Tier List | Once Human|Game8 (2025)

FAQs

What is the best memetic specialization once human? ›

Once Human Best Memetic Specializations Summary
Memetic SpecializationLevels
Electric Drill: Treasure Hunter20 - 35
Supplies Workbench: Healing Boost20 - 35
Backpack Expansion5 - 15
Harvesting Sickle5 - 15
2 more rows
Aug 5, 2024

Can you unlock all memetics in Once Human? ›

You can't unlock everything under the different Memetics branches right away. You will need to start from the top of each branch, and make your way down in order to unlock the more complex and powerful Memetics. The different branches are also segmented into different stages.

What is the memetic specialization for acid in once human? ›

Memetic Specialization gives players a few options to create acid in their territory: Sulphur Chemist and Art of Stardust. The Memetic Specialization option pool is random for each player.

What to focus on Once Human? ›

You can do a lot in Once Human, but you should focus on the main story for at least the first couple of dungeons. This will show you the basic gameplay loop, introduce you to how the world works, and help you find gear.

What is the best MTF in SCP? ›

Alpha-1 is the highest-ranking MTF within the SCP Foundation and is tasked with direct involvement in high-priority and high-risk operations, and as such, is the only MTF sub-unit that requires players to possess Level-3 Security Clearance to be able to play.

What are the memetic specialization nodes in Once Human? ›

Memetic Specializations. There are four branches of Memetic Specializations: Building, Crafting, Gathering, and Management. Every 5 levels, a Memetic Specialization node will be unlocked, which offers a choice among 4 randomly generated Specializations.

What is the best pickaxe in Once Human? ›

The Tungsten Alloy Pickaxe is the strongest pickaxe in Once Human. It unlocks when you learn how to craft Tungsten Ingots and is needed to mine Gold Ore. The following materials are needed to craft a Tungsten Alloy Pickaxe: 10 Tungsten Ingots.

How to get memetics fast Once Human? ›

How To Get Memetic Points In Once Human. The main way players will be getting Meme Points is by leveling up. Every time players level up, they will be given a few Meme Points, with a lot being obtained early on and the pace slowing down as players reach higher levels.

What memetics to unlock? ›

  1. 1 Rocket Launchers.
  2. 2 Dishes And Advanced Cooking. ...
  3. 3 Garage And Modifications. ...
  4. 4 Solar Generator. ...
  5. 5 Synthesis Bench. ...
  6. 6 Intermediate Gear Bench. ...
  7. 7 Bronze Crafting And Pickaxes. Will Set You On The Right Path To Tier Scaling. ...
  8. 8 Disassembly Bench. The First Thing You Need To Unlock. ...
Jul 17, 2024

What are the memetics in Once Human? ›

Memetics grant Formulas that players can use to build and craft in Once Human. Memetics are obtained by spending Meme Points (also known as Ciphers), which players earn by Leveling, completing Season Goals (Phase Rewards), and occasionally by completing Story Tasks.

Where is the best Acid farm in Once Human? ›

The Greywater Industrial Zone is located in the northern part of the Iron River area, and this is by far the best place to farm Acid in Once Human. From the southern entrance, go to the center and take down several enemies, then turn to the east and follow the building lines to the warehouse area.

What specialization is Acid in Once Human? ›

The specialization you need is Sulfur Chemist. This will give you the ability to craft acid using a Synthesis Bench with Sulfur and Energy Links. The Synthesis Bench can be unlocked under the Crafting branch of your Memetics menu.

Why is Acid so important in once humans? ›

Acid is an extremely important material in Once Human, as it is used to create Gunpowder (and ammunition by extension). Fortunately, there are several ways to quickly obtain Acid in Once Human, and this guide details two activities that fans who are short on the material should pursue.

What is the acid specialization in Once Human? ›

The specialization you need is Sulfur Chemist. This will give you the ability to craft acid using a Synthesis Bench with Sulfur and Energy Links. The Synthesis Bench can be unlocked under the Crafting branch of your Memetics menu.

What are the skill specializations in Once Human? ›

These include physical strength, endurance, crafting, resource gathering, and even Stardust manipulation. Every five levels you get to choose from a selection of randomized Memetic Specializations. These are powerful buffs that can enhance your Meta-Human's abilities.

What is precious metal refining specialization Once Human? ›

Precious Metal Refining is a Memetic Specialization. Smelt Gold and Silver Ores into Ingots using the Electric Furnace. The Ingots can be sold for a large number of Energy Links.

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